FAAH/MAGL-IN-2
FAAH/MAGL-IN-2 is a potent, reversible, orally active, and cross the blood-brain barrier FAAH and MAGL inhibitor with IC50s of 11 nM and 36 nM (Kis of 28 nM and 60 nM), respectively . FAAH/MAGL-IN-2 has the potential to research neuropathic pain without causing locomotion impairment[1].
Product Specifications
CAS Number
2765077-82-3
UNSPSC
12352005
Target
FAAH; MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/faah-magl-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C\C1=C(Cl)C=CC=C1Cl)NC2=CC=C(S(=O)(C)=O)C=C2
Molecular Formula
C15H13Cl2N3O3S
Molecular Weight
386.25
References & Citations
[1]Jaiswal S, et al. Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. Bioorg Med Chem. 2022; 60:116698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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