FAAH/MAGL-IN-1
FAAH/MAGL-IN-1 (compound SIH 3) is a potent FAAH and MAGL inhibitor with IC50s of 31 nM and 29 nM, respectively. FAAH/MAGL-IN-1 has the potential for the research of neuropathic pain[1].
Product Specifications
UNSPSC
12352005
Target
FAAH; MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/faah-magl-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C1C(NC2=CC(Cl)=CC=C2\1)=O)C3=C(O)C=CC=C3Cl
Molecular Formula
C15H9Cl2N3O3
Molecular Weight
350.16
References & Citations
[1]Jaiswal S, et al. Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. Bioorg Med Chem. 2022; 60:116698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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