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FAAH/MAGL-IN-1

FAAH/MAGL-IN-1 (compound SIH 3) is a potent FAAH and MAGL inhibitor with IC50s of 31 nM and 29 nM, respectively. FAAH/MAGL-IN-1 has the potential for the research of neuropathic pain[1].

Product Specifications

UNSPSC

12352005

Target

FAAH; MAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/faah-magl-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C1C(NC2=CC(Cl)=CC=C2\1)=O)C3=C(O)C=CC=C3Cl

Molecular Formula

C15H9Cl2N3O3

Molecular Weight

350.16

References & Citations

[1]Jaiswal S, et al. Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. Bioorg Med Chem. 2022; 60:116698.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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