CDK4/6-IN-7
Product Specifications
UNSPSC Description
CDK4/6-IN-7 is a potent, selective and orally active CDK4/6 inhibitor, with IC50s of 1.58 and 4.09 nM, respectively. CDK4/6-IN-7 can be used for the research of breast cancer[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk4-6-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1Cl)NNC(N2CCC[C@@H]2C(NC3=CC=CN=C3)=O)=O
Molecular Weight
387.82
References & Citations
[1]Liang JW, et, al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143257/CDK4-6-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143257/
Clinical Information
No Development Reported
CAS Number
2649120-20-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
