CEase-IN-1
Product Specifications
UNSPSC Description
CEase-IN-1 (Compound A1H3) is a potent and selective cholesterol esterase (CEase) inhibitor with an IC50 of 0.36 μM. CEase-IN-1 can be used for the research of hypercholesterolemia[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cease-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(COC1=CC=C(C(F)(F)F)C=C1)N/N=C/CCC
Molecular Weight
288.27
References & Citations
[1]Zhao S, et al. Identification and synthesis of selective cholesterol esterase inhibitor using dynamic combinatorial chemistry. Bioorg Chem. 2022 Feb;119:105520.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143252/CEase-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143252/
Clinical Information
No Development Reported
CAS Number
2985688-68-2
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