Tubulin inhibitor 12
Tubulin inhibitor 12 (Hit 9) is a novel tubulin inhibitor (IC50=25.3 μM) . Tubulin inhibitor 12 shows anti-tumor activity and anti-proliferative activity[1].
Product Specifications
CAS Number
92575-00-3
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-12.html
Solubility
10 mM in DMSO
Smiles
CN(C(C1=CC(C2=CC=CC=C2)=NC3=CC=CC=C31)=O)CC4=CC=CC=C4
Molecular Formula
C24H20N2O
Molecular Weight
352.43
References & Citations
[1]Wei Liu, et al. Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation. Bioorg Chem. 2022 Jan;118:105486.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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