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MtMetAP1-IN-1

MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1) . MtMetAP1-IN-1 exerts antimycobacterial activity[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mtmetap1-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC=CN=C1NC(C2=C(C=CC=C2)Br)=O)NC3=NC=CS3

Molecular Formula

C15H10BrN5O2S

Molecular Weight

404.24

References & Citations

[1]Juhás M, et al. Design, synthesis and biological evaluation of substituted 3-amino-N- (thiazol-2-yl) pyrazine-2-carboxamides as inhibitors of mycobacterial methionine aminopeptidase 1. Bioorg Chem. 2022 Jan;118:105489.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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