Monoamine Oxidase B inhibitor 1

Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor with an IC50 of 0.02 nM. Monoamine Oxidase B inhibitor 1 has antioxidant and anti-neuroinflammatory activities. Monoamine Oxidase B inhibitor 1 can across the blood-brain barrier (BBB), and can be used for Parkinson’s disease study[1].

Product Specifications

CAS Number

[2807477-70-7]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/monoamine-oxidase-b-inhibitor-1.html

Solubility

10 mM in DMSO

Smiles

C=CCC1OC(C2=CC(OCC3=CC=C(C=C3)F)=CC=C21)=O

Molecular Formula

C18H15FO3

Molecular Weight

298.31

References & Citations

[1]Qing Song, et al. 6-Benzyloxyphthalides as selective and reversible monoamine oxidase B inhibitors with antioxidant and anti-neuroinflammatory activities for Parkinson's disease treatment. Bioorg Chem. 2022 Mar;120:105623.