Monoamine Oxidase B inhibitor 1
Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor with an IC50 of 0.02 nM. Monoamine Oxidase B inhibitor 1 has antioxidant and anti-neuroinflammatory activities. Monoamine Oxidase B inhibitor 1 can across the blood-brain barrier (BBB), and can be used for Parkinson’s disease study[1].
Product Specifications
CAS Number
[2807477-70-7]
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/monoamine-oxidase-b-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
C=CCC1OC(C2=CC(OCC3=CC=C(C=C3)F)=CC=C21)=O
Molecular Formula
C18H15FO3
Molecular Weight
298.31
References & Citations
[1]Qing Song, et al. 6-Benzyloxyphthalides as selective and reversible monoamine oxidase B inhibitors with antioxidant and anti-neuroinflammatory activities for Parkinson's disease treatment. Bioorg Chem. 2022 Mar;120:105623.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
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