FY-56
Product Specifications
UNSPSC Description
FY-56 is a highly potent and selective LSD1/KDM1A inhibitor (IC50=42 nM) and exhibits high selectivity over MAO-A/B. FY-56 induces differentiation of MOLM-13 and MV4-11 cell and has the potential for AML research[1].
Target Antigen
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fy-56.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C(C13NCCC4=CC(O)=C(C=C43)O)C=CC=C2)CC5=C(C=CC=C5)F
Molecular Weight
390.41
References & Citations
[1]Chao Yang, et al. Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment. Bioorg Chem. 2022 Mar; 120:105596
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143238/FY-56-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143238/
Clinical Information
No Development Reported
Curated Selection
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