ATX inhibitor 11
ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].
Product Specifications
CAS Number
2485779-27-7
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/atx-inhibitor-11.html
Purity
99.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCC1=C(N2C=C(C=C(C2=N1)C)C3=CC=C(C=C3)C(N4CCN(CC4)CCO)=O)NC(OCC5=CC6=C(OCO6)C=C5)=O
Molecular Formula
C32H35N5O6
Molecular Weight
585.65
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin
Available Sizes
Frequently Asked Questions
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