Antibacterial agent 73

Antibacterial agent 73 (compound 7a) is a potent antimicrobial agent. Antibacterial agent 73 exhibits very good antitubercular activity (MIC=0.65 µg/mL) against Mtb H37Rv. Antibacterial agent 73 shows good activity against fungal and bacterial. Antibacterial agent 73 also shows cytotoxicity in MCF-7 breast cancer cell lines, with IC50 of 8.20 μM[1].

Product Specifications

CAS Number

[414885-92-0]

UNSPSC

12352005

Target

Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-73.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=CC=C1N2CCN(CC3=CC=CO3)CC2

Molecular Formula

C15H17FN2O

Molecular Weight

260.31

References & Citations

[1]Mekonnen Sanka B, et al. Design, synthesis, biological screening and molecular docking studies of novel multifunctional 1,4-di (aryl/heteroaryl) substituted piperazine derivatives as potential antitubercular and antimicrobial agents. Bioorg Chem. 2022 Feb;119:105568. \