Antibacterial agent 73
Antibacterial agent 73 (compound 7a) is a potent antimicrobial agent. Antibacterial agent 73 exhibits very good antitubercular activity (MIC=0.65 µg/mL) against Mtb H37Rv. Antibacterial agent 73 shows good activity against fungal and bacterial. Antibacterial agent 73 also shows cytotoxicity in MCF-7 breast cancer cell lines, with IC50 of 8.20 μM[1].
Product Specifications
CAS Number
[414885-92-0]
UNSPSC
12352005
Target
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-73.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=CC=C1N2CCN(CC3=CC=CO3)CC2
Molecular Formula
C15H17FN2O
Molecular Weight
260.31
References & Citations
[1]Mekonnen Sanka B, et al. Design, synthesis, biological screening and molecular docking studies of novel multifunctional 1,4-di (aryl/heteroaryl) substituted piperazine derivatives as potential antitubercular and antimicrobial agents. Bioorg Chem. 2022 Feb;119:105568. \
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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