TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a new type of antineuroinflammatory agent by suppressing TLR4/NF-kB/MAPK pathways.
Product Specifications
CAS Number
2767567-26-8
UNSPSC
12352005
Target
NF-κB; p38 MAPK; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tlr4-nf-κb-mapk-in-1.html
Solubility
10 mM in DMSO
Smiles
C=C1C(O[C@@H]2CC(CBr)=C([C@H]([C@H]12)OC(C)=O)[C@H](CCCOC(C)=O)C)=O
Molecular Formula
C19H25BrO6
Molecular Weight
429.30
References & Citations
[1]Tang JJ, et al. 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways. Eur J Med Chem. 2021 Nov 15;224:113713.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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