UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2) -containing ligand, has a KD for CBX5 of 5.7 μM[1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unc6212-kme2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=COC=C1)NC(C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C(OC)=C2)OC)C(N[C@H](C(N[C@H](C(N)=O)CO)=O)CCCCN(C)C)=O)=O)=O)C(C3=CC=CC=C3)O
Molecular Formula
C39H53N7O11
Molecular Weight
795.88
References & Citations
[1]Kean KM, et al. Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. J Med Chem. 2022;65 (3) :2646-2655.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL700444V 500 µL Each
Mas1l Rat shRNA Lentiviral Particle (Locus ID 404641)
Sign In for Pricing
View Details 