ALK5-IN-6
ALK5-IN-6 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-6 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 1) [1].
Product Specifications
CAS Number
2657720-04-0
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alk5-in-6.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(OC3=CN(C4CC4)N=C3C5CCOCC5)C=CN=C2C=C1OCCCN6CCOCC6
Molecular Formula
C28H36N4O5
Molecular Weight
508.61
References & Citations
[1]Tang Feng, et al. Pyrazoles. Patent WO2021129621A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![(5E)-5-(3-Bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol](https://cdn.genprice.uk/products/572/2197011482476/imageurl/trc-b471365-2.5mg.webp)
(5E)-5-(3-Bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol
