KRAS G12C inhibitor 46

[2573769-23-8]

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/kras-g12c-inhibitor-46.html

10 mM in DMSO

O=C1N2C3=NC(C4=C(F)C=CC=C4NCCCC5=CC=NC(C(C)C)=C52)=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1

C32H33F2N7O2

585.65

[1]Li Qiu, et al. Macrocyclic compoung serving as Kras inhibitor. WO2021147967A1.

Room temperature

Reference compound1

No Development Reported

K-Ras