KRAS G12C inhibitor 46

KRAS G12C inhibitor 46 (compound WX003) is a potent KRAS G12C inhibitor[1].

Product Specifications

CAS Number

[2573769-23-8]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-46.html

Solubility

10 mM in DMSO

Smiles

O=C1N2C3=NC(C4=C(F)C=CC=C4NCCCC5=CC=NC(C(C)C)=C52)=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1

Molecular Formula

C32H33F2N7O2

Molecular Weight

585.65

References & Citations

[1]Li Qiu, et al. Macrocyclic compoung serving as Kras inhibitor. WO2021147967A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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