KRAS G12C inhibitor 46
KRAS G12C inhibitor 46 (compound WX003) is a potent KRAS G12C inhibitor[1].
Product Specifications
CAS Number
[2573769-23-8]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-46.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C3=NC(C4=C(F)C=CC=C4NCCCC5=CC=NC(C(C)C)=C52)=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1
Molecular Formula
C32H33F2N7O2
Molecular Weight
585.65
References & Citations
[1]Li Qiu, et al. Macrocyclic compoung serving as Kras inhibitor. WO2021147967A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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