KRAS G12C inhibitor 45
KRAS G12C inhibitor 45 (compound 78) is a potent KRAS G12C inhibitor[1].
Product Specifications
CAS Number
2670380-74-0
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-45.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C(C=CC=C2C(C)C)S(C)(=O)=O)C3=NC(C4=C(C=CC=C4O)F)=C(F)C=C3C(N5[C@H](CN([C@@H](C5)C)C(C=C)=O)C)=N1
Molecular Formula
C32H33F2N5O5S
Molecular Weight
637.70
References & Citations
[1]LV Binhua, et al. Aryl or heteroaryl pyridone or pyrimidine derivative preparation method and use thereof. WO2021143693A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Frequently Asked Questions
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