DNA-PK-IN-2
DNA-PK-IN-2 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) . DNA-PK-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2021136462A1, compound 1) [1].
Product Specifications
CAS Number
[2665720-22-7]
UNSPSC
12352005
Target
DNA-PK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-pk-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C2=CN=C(NC3=CC4=C(C=C3C)OCC4)N=C2N1C5CCOCC5
Molecular Formula
C20H23N5O3
Molecular Weight
381.43
References & Citations
[1]Yonggang Wei, et al. Furan derivatives and their applications in medicine. Patent WO2021136462A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Tubulin-specific chaperone coFactor E-Like protein (TBCEL) Rat ELISA Kit
