DNA-PK-IN-2
DNA-PK-IN-2 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) . DNA-PK-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2021136462A1, compound 1) [1].
Product Specifications
CAS Number
[2665720-22-7]
UNSPSC
12352005
Target
DNA-PK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-pk-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C2=CN=C(NC3=CC4=C(C=C3C)OCC4)N=C2N1C5CCOCC5
Molecular Formula
C20H23N5O3
Molecular Weight
381.43
References & Citations
[1]Yonggang Wei, et al. Furan derivatives and their applications in medicine. Patent WO2021136462A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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