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RORγt modulator 4

RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146) [1].

Product Specifications

CAS Number

2188177-73-1

UNSPSC

12352005

Target

ROR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rorγt-modulator-4.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC2=C(C=C1)N(C3=CC(C4CC4)=CC(C)=C3)CCO2)NCC5=CC=C(S(=O)(C)=O)C=C5

Molecular Formula

C26H27N3O4S

Molecular Weight

477.58

References & Citations

[1]Satoshi Yamamoto, et al. Heterocyclic compounds with an ror (gamma) t modulating activity. WO2018030550A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RORγ

Frequently Asked Questions

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