RORγt modulator 4
RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146) [1].
Product Specifications
CAS Number
2188177-73-1
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rorγt-modulator-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC2=C(C=C1)N(C3=CC(C4CC4)=CC(C)=C3)CCO2)NCC5=CC=C(S(=O)(C)=O)C=C5
Molecular Formula
C26H27N3O4S
Molecular Weight
477.58
References & Citations
[1]Satoshi Yamamoto, et al. Heterocyclic compounds with an ror (gamma) t modulating activity. WO2018030550A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RORγ
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