RORγt inhibitor 2
RORγt inhibitor 2 (Compound 119) is a potent RORγt inhibitor with an IC50 of 9.2 nM. RORγt inhibitor 2 can be used for the research of cancer, inflammation or autoimmune diseases mediated by RORγt[1].
Product Specifications
CAS Number
2673278-10-7
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/rorγt-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
FC(F)OC[C@H]1N(C2=CC=C(C=C2)C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CCO)=O)C[C@H](C1)OC4=CC=C(C=C4)OC(F)(F)F
Molecular Formula
C31H33F5N2O7S
Molecular Weight
672.66
References & Citations
[1]RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF. WO2021139599A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
