IDO-IN-16
IDO-IN-16 (compound 5) is an IDO inhibitor, with an IC50 of 36 nM[1]. IDO-IN-16 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2663591-36-2]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C)=C1CCC(CC/1)C2=C(N)N=C(C(F)(F)F)C=C2)NC3=CN=C(C=C3)C#C
Molecular Formula
C22H21F3N4O
Molecular Weight
414.42
References & Citations
[1]DAI GUANGXI, et al. NOVEL AMIDE COMPOUNDS AND USES THEREOF. Patent WO2021136464A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142933/IDO-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142933/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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