IDO-IN-16

IDO-IN-16 (compound 5) is an IDO inhibitor, with an IC50 of 36 nM[1]. IDO-IN-16 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2663591-36-2]

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido-in-16.html

Solubility

10 mM in DMSO

Smiles

O=C(/C(C)=C1CCC(CC/1)C2=C(N)N=C(C(F)(F)F)C=C2)NC3=CN=C(C=C3)C#C

Molecular Formula

C22H21F3N4O

Molecular Weight

414.42

References & Citations

[1]DAI GUANGXI, et al. NOVEL AMIDE COMPOUNDS AND USES THEREOF. Patent WO2021136464A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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