ATM-IN-1
ATM-IN-1 is a potent inhibitor of ATM. ATM is located mainly in the nucleus and microsomes and is involved in cell cycle progression and in the cell cycle checkpoint response to DNA damage. ATM-IN-1 has the potential for the research of cancer and neurology diseases (extracted from patent WO2021139814A1, compound 3) [1].
Product Specifications
CAS Number
[2662761-76-2]
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atm-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N1N2CCOCC2)N(C3CC3)C4=C1C5=CC(C6=CC=C(OCCCN7CCCCC7)N=C6)=CC=C5N=C4
Molecular Formula
C30H36N6O3
Molecular Weight
528.65
References & Citations
[1]Wenyuan Qian, et al. Quinoline and imidazole compounds and their applications. Patent WO2021139814A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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