MAT2A-IN-3
Product Specifications
UNSPSC Description
MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265)[1].
Target Antigen
Somatostatin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mat2a-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(OC(F)F)C=C2)=C3N=C(OCC(F)(F)F)N=CC3=CN1C4=CC5=CN(C)N=C5C=C4
Molecular Weight
517.41
References & Citations
[1]Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2019191470A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142930/MAT2A-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142930/
Clinical Information
No Development Reported
CAS Number
2377493-28-0
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