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MAT2A-IN-1

MAT2A-IN-1 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-1 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021139775A1, compound 64) [1].

Product Specifications

CAS Number

2667053-18-9

UNSPSC

12352005

Target

Somatostatin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mat2a-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C2=CC3=CN(CCN4CCOCC4)N=C3C=C2)=CC5=C(N1C6=CC=C(C=C6)OC(F)F)N=C(OCC)N=C5

Molecular Formula

C29H28F2N6O4

Molecular Weight

562.57

References & Citations

[1]Li Zhen, et al. Pyridone compounds and applications. Patent WO2021139775A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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