ER degrader 3

ER degrader 3 is a potent degrader of estrogen receptor (ER) . The estrogen signaling system plays an important role in regulating cell growth, differentiation and apoptosis. ER degrader 3 has the potential for the research of cancer diseases (extracted from patent WO2018233591A1, compound 1) [1].

Product Specifications

CAS Number

[2254818-47-6]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/er-degrader-3.html

Solubility

10 mM in DMSO

Smiles

NCCCC[C@H](N)C(O)=O.C[C@H]1N(C2=CC=C(C3CC3)C=C2)[C@@](C4=CC=C(C=C4)/C=C/C(O)=O)([H])C5=CC=C(C6=CN(N=C6)CC)C=C5C1

Molecular Formula

C39H47N5O4

Molecular Weight

649.82

References & Citations

[1]Lingfeng You, et al. A kind of salt of benzopiperidine derivatives, its crystal form and salt, the preparation method of its crystal form. Patent WO2018233591A1.