ATR-IN-8
ATR-IN-8 is a potent inhibitor of ATR. ATR is a key enzyme in the homologous recombination repair pathway and belongs to the PIKK family. ATR-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021143821A1, compound 3) [1].
Product Specifications
CAS Number
[2672511-20-3]
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-8.html
Solubility
10 mM in DMSO
Smiles
N=S1(C2(CC2)C3=NC(C4=C5C(NC=C5)=NC=C4)=NC(N6[C@@H](COCC6)C)=C3C1)=O
Molecular Formula
C20H22N6O2S
Molecular Weight
410.49
References & Citations
[1]Li Xin, et al. Thickened heteroaryl derivatives, their preparation methods and their application in medicine. Patent WO2021143821A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![MYBPC3 Mouse Monoclonal Antibody [Clone ID: OTI1A5]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
