ATR-IN-8
Product Specifications
UNSPSC Description
ATR-IN-8 is a potent inhibitor of ATR. ATR is a key enzyme in the homologous recombination repair pathway and belongs to the PIKK family. ATR-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021143821A1, compound 3)[1].
Target Antigen
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-8.html
Solubility
10 mM in DMSO
Smiles
N=S1(C2(CC2)C3=NC(C4=C5C(NC=C5)=NC=C4)=NC(N6[C@@H](COCC6)C)=C3C1)=O
Molecular Weight
410.49
References & Citations
[1]Li Xin, et al. Thickened heteroaryl derivatives, their preparation methods and their application in medicine. Patent WO2021143821A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142924/ATR-IN-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142924/
Clinical Information
No Development Reported
CAS Number
2672511-20-3
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