AR antagonist 2
AR antagonist 2 (compound 58) is a potent androgen receptor (AR) inhibitor with an IC50 of 0.95 μM. AR antagonist 2 has the potential for cancer research[1].
Product Specifications
CAS Number
2275752-15-1
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ar-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(N(C(N(C2=CN(C(C(F)=C2)=NC(CC)=C3)C3=O)C4(C)C)=S)C4=O)C=C1Cl
Molecular Formula
C22H17ClFN5O2S
Molecular Weight
469.92
References & Citations
[1]Chenli Shen, et al. Diaryl thiohydantoins as androgen receptor antagonists. WO2019029521A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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