THR-β agonist 4
THR-β agonist 4 is a potent agonist of THR-β. THR-β agonist 4 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021143706A1, compound 72) [1].
Product Specifications
CAS Number
2673409-25-9
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/thr-β-agonist-4.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(N(C2=CC(Cl)=C(C(Cl)=C2)OC3=NC=C(C(S(=O)(NC)=O)=C3)O)N=C1C(F)F)=O
Molecular Formula
C16H11Cl2F2N5O6S
Molecular Weight
510.26
References & Citations
[1]Jingye Zhou, et al. Substituted triazinones as thyroid hormone receptor agonists. Patent WO2021143706A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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