Maximiscin
Maximiscin, a fungal metabolite, induces DNA damage and shows selective cytotoxic activity against a subtype of triple-negative breast cancer.
Product Specifications
CAS Number
1612154-44-5
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maximiscin.html
Solubility
10 mM in DMSO
Smiles
C=C[C@H]1[C@H](C2=C(O)C=CN(O[C@@H]3C(C(OC)=O)=C[C@H]([C@H]([C@H]3O)O)O)C2=O)[C@H](C[C@H](C1)C)C
Molecular Formula
C23H31NO8
Molecular Weight
449.49
References & Citations
[1]Robles AJ, et al. Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer. J Nat Prod. 2016 Jul 22;79 (7) :1822-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
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