M-MoDE-A (2)
M-MoDE-A (2) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR) .
Product Specifications
CAS Number
2378837-56-8
UNSPSC
12352005
Target
LYTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/m-mode-a-2.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@H]([C@H]([C@H]([C@H](O1)CO)O)O)[C@@H]1OCCOCCOCCNC(CCOCC(COCCC(NCCOCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(C)=O)=O)(COCCC(NCCOCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)=O)NC(CNC(CCCOC4=CC5=C(C=C4)N=C(C6=CN(C7=CC(F)=C(C=C7)O)N=N6)C=C5)=O)=O)=O)=O
Molecular Formula
C78H119FN12O34
Molecular Weight
1787.84
References & Citations
[1]Caianiello DF, et al. Bifunctional small molecules that mediate the degradation of extracellular proteins. Nat Chem Biol. 2021 Sep;17 (9) :947-953.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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