RORγt inverse agonist 26
Product Specifications
UNSPSC Description
RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) [1].
Target Antigen
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rorγt-inverse-agonist-26.html
Solubility
10 mM in DMSO
Smiles
FC(C=C(C=C1)C(C(F)(F)F)(O)C(F)(F)F)=C1C(C=C2)=CC=C2NC([C@H]3C4=CC=C(S(C)(=O)=O)C=C4CN3C(C)=O)=O
Molecular Weight
618.52
References & Citations
[1]Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142806/RORγt-inverse-agonist-26-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142806/
Clinical Information
No Development Reported
CAS Number
2738333-10-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Cytochrome b245 alpha Antibody (CS9) [PerCP]](https://cdn.genprice.uk/genprice/genprice5.png)
