MAO A/HDAC-IN-1
MAO A/HDAC-IN-1 is a dual inhibitor of monoamine oxidase A (MAO A) and HDAC. MAO A/HDAC-IN-1 can be used for glioma research[1]. MAO A/HDAC-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
3031466-56-2
UNSPSC
12352005
Target
HDAC; Monoamine Oxidase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mao-a-hdac-in-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(C=CC(NCC2=CC=C(C=C2)C(NO)=O)=C1)OCCCN(CC#C)C
Molecular Formula
C21H24ClN3O3
Molecular Weight
401.89
References & Citations
[1]Samir Mehndiratta, et al. N-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment. J Med Chem. 2022 Feb 10;65 (3) :2208-2224.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A
Frequently Asked Questions
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