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BRD4 D1-IN-1

BRD4 D1-IN-1 is a selective BRD4 D1 inhibitor (IC50[1].

Product Specifications

CAS Number

2863623-98-5

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd4-d1-in-1.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3[C@@H]4CN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C

Molecular Formula

C32H37F3N6O

Molecular Weight

578.67

References & Citations

[1]Cui H, et al. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 2022;65 (3) :2342-2360.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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