DCN1-UBC12-IN-3
DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].
Product Specifications
CAS Number
2374827-45-7
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dcn1-ubc12-in-3.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C4C=CC=CC4=C3)N=C1SC5=NN=NN5CCN(C)C
Molecular Formula
C30H30N8O3S2
Molecular Weight
614.74
References & Citations
[1]He ZX, et al. Discovery of Potent and Selective 2- (Benzylthio) pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65 (1) :163-190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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