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DCN1-UBC12-IN-3

DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].

Product Specifications

CAS Number

2374827-45-7

UNSPSC

12352005

Target

E1/E2/E3 Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/dcn1-ubc12-in-3.html

Solubility

10 mM in DMSO

Smiles

N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C4C=CC=CC4=C3)N=C1SC5=NN=NN5CCN(C)C

Molecular Formula

C30H30N8O3S2

Molecular Weight

614.74

References & Citations

[1]He ZX, et al. Discovery of Potent and Selective 2- (Benzylthio) pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65 (1) :163-190.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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