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EGFR-IN-23

EGFR-IN-23 is a potent EGFR TKI (tyrosine kinase inhibitor) with an IC50 of 8.05 nM for BaF3/EGFR-DEL19/T790M/C797S cell (WO2021244502A1, compound 8) [1].

Product Specifications

CAS Number

2747133-37-3

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-23.html

Solubility

10 mM in DMSO

Smiles

CN1N=CC(C2=C(N3CCC(CN4CCOCCC4)CC3)C=C(OC)C(NC5=NC=C(Br)C(NC6=CC=C7N=CC=NC7=C6P(C)(C)=O)=N5)=C2)=C1

Molecular Formula

C36H44BrN10O3P

Molecular Weight

775.68

References & Citations

[1]Polyaryl compound and use. WO2021244502A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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