EGFR-IN-21
EGFR-IN-21 is a potent EGFR inhibtior with an IC50 of 0.38 nM. EGFR-IN-21 has antitumor activity[1].
Product Specifications
CAS Number
2648206-31-7
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-21.html
Solubility
10 mM in DMSO
Smiles
O=P(C)(C)C1=C2C=CC=CC2=NC=C1NC3=NC(NC4=CC(C5=CN(C)N=C5)=C(N6CCC(CC6)N7CCN(CC7)C)C=C4OC)=NC=C3Br
Molecular Formula
C36H44BrN10O2P
Molecular Weight
759.68
References & Citations
[1]Lei Liu, et al. Polyaryl compounds as EGFR kinase inhibitors. WO2021104441.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
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