ATR-IN-5
ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24) [1].
Product Specifications
CAS Number
2601571-19-9
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-5.html
Solubility
10 mM in DMSO
Smiles
CNC1=NC2=CC=CC=C2N1C3=NC(N4[C@@H](COCC4)C)=CC(C5=C(N(C6CCNCC6)N=C5C)C(F)(F)F)=N3
Molecular Formula
C27H32F3N9O
Molecular Weight
555.60
References & Citations
[1]Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent CN112047938A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Cardiac Troponin T (TNNT2) Mouse Monoclonal Antibody [Clone ID: OTI7A1]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
Cardiac Troponin T (TNNT2) Mouse Monoclonal Antibody [Clone ID: OTI7A1]
Rat Very low-density lipoprotein receptor (VLDLR) ELISA Kit
Rat Very low-density lipoprotein receptor (VLDLR) ELISA Kit
Rat Very low-density lipoprotein receptor (VLDLR) ELISA Kit
Rat Very low-density lipoprotein receptor (VLDLR) ELISA Kit