BAY 1217224
BAY 1217224 is a neutral, non-proagent Thrombin inhibitor with good oral pharmacokinetics.
Product Specifications
CAS Number
1639886-32-0
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bay-1217224.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C(N=C(O2)N[C@@H](C3=CC(Cl)=CC=C3)CF)=CC(C(N4[C@H](CO[C@H](C4)C)CCO)=O)=C1
Molecular Formula
C24H27ClFN3O5
Molecular Weight
491.94
References & Citations
[1]Hillisch A, et al. Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics. J Med Chem. 2020 Nov 12;63 (21) :12574-12594.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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