PDE2A-IN-1
Product Specifications
UNSPSC Description
PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC50 value of 1.3 nM.
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pde2a-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1[C@](CN(C2=CC(C3=CC=CC=C3)=CC=N2)CC1)([H])C4=CC(C(F)F)=NC5=NC=NN45
Molecular Weight
420.46
References & Citations
[1]Tresadern G, et al. [1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration. J Med Chem. 2020 Nov 12;63(21):12887-12910.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142660/PDE2A-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142660/
Clinical Information
No Development Reported
Curated Selection
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