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PI3Kδ-IN-9

PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC50 value of 3.8 nM.

Product Specifications

CAS Number

2135922-40-4

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3kδ-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@](C)(NCC(C)(F)C)C2=CC(C3=C4N=C(C5=CN=C(C)N=C5)N(CC)C4=NC=N3)=CN=C2N1

Molecular Formula

C24H26FN9O

Molecular Weight

475.52

References & Citations

[1]Methot JL, et al. Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors. ACS Med Chem Lett. 2020 Nov 19;11 (12) :2461-2469.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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