TP0591816
Product Specifications
UNSPSC Description
TP0591816 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins (wild-type, EC50 = 0.27 nM; D486N-mutant, EC50 = 0.70 nM).
Target Antigen
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tp0591816.html
Solubility
10 mM in DMSO
Smiles
CN1C2=CC([C@]3([H])C[C@H](C3)O)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(Cl)=CC=C6OCC(NCC1)=O)=O)=NN24
Molecular Weight
539.03
References & Citations
[1]Yamaguchi-Sasaki T, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142645/TP0591816-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142645/
Clinical Information
No Development Reported
CAS Number
2448519-26-2
Curated Selection
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