BLT2 probe 1

BLT2 probe 1 (compound 13) is a fluorescent probe based on the synthetic BLT2 agonist CAY10583. BLT2 is a promising target for diabetic wound healing and gastrointestinal lesions. BLT2 probe 1 is suitable to investigate the pharmacology of BLT2 receptor ligands in a variety of assay systems[1].

Product Specifications

CAS Number

[2893803-05-7]

UNSPSC

12352005

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/blt2-probe-1.html

Solubility

10 mM in DMSO

Smiles

S=C(NC1=CC(C(O)=O)=C(C=C1)C2=C(C(OC3=C2C=CC(O)=C3)=C4)C=CC4=O)NCCOCCOCCOCCC(N(C5=CC=CC=C5)CC6=CC=C(C7=C(C(O)=O)C=CC=C7)C=C6)=O

Molecular Formula

C50H45N3O11S

Molecular Weight

895.97

References & Citations

[1]Heering J, et al. Development and Characterization of a Fluorescent Ligand for Leukotriene B4 Receptor 2 in Cells and Tissues. J Med Chem. 2022;65 (3) :2023-2034.