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EGFR-IN-27

EGFR-IN-27 is a potent EGFR inhibitor with IC50s of [1].

Product Specifications

CAS Number

[2752328-62-2]

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-27.html

Solubility

10 mM in DMSO

Smiles

O=P(C)(C)C1=C2N=CC=NC2=CC=C1NC3=NC(NC4=C(OC)C=C(N5CCC(CC5)N6CCN(CC6)C)C(CC)=C4)=NC=C3C=C

Molecular Formula

C35H46N9O2P

Molecular Weight

655.77

References & Citations

[1]Alkenyl pyrimidine compound, preparation method therefor, and application thereof. WO2021249324A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EGFR/ErbB1/HER1

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