EGFR-IN-27
EGFR-IN-27 is a potent EGFR inhibitor with IC50s of [1].
Product Specifications
CAS Number
[2752328-62-2]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-27.html
Solubility
10 mM in DMSO
Smiles
O=P(C)(C)C1=C2N=CC=NC2=CC=C1NC3=NC(NC4=C(OC)C=C(N5CCC(CC5)N6CCN(CC6)C)C(CC)=C4)=NC=C3C=C
Molecular Formula
C35H46N9O2P
Molecular Weight
655.77
References & Citations
[1]Alkenyl pyrimidine compound, preparation method therefor, and application thereof. WO2021249324A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
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