EGFR-IN-25
Product Specifications
UNSPSC Description
EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-25.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(C2=CC=CC3=C2C=CN3)=C(NC4CCOCC4)N=C1NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5)N
Molecular Weight
609.76
References & Citations
[1]New pyrazine compound. WO2021244505A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142517/EGFR-IN-25-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142517/
Clinical Information
No Development Reported
CAS Number
2749562-63-6
Curated Selection
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