EGFR-IN-25
EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].
Product Specifications
CAS Number
[2749562-63-6]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-25.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(C2=CC=CC3=C2C=CN3)=C(NC4CCOCC4)N=C1NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5)N
Molecular Formula
C34H43N9O2
Molecular Weight
609.76
References & Citations
[1]New pyrazine compound. WO2021244505A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7178258 Inquire
Rabbit anti-Escherichia coli O127:H6 (strain E2348/69/EPEC) LLDD Polyclonal Antibody
Ask
View Details 
abx252822-02 5x 96 Tests
Human Nuclear Mitotic Apparatus Protein 1 (NUMA1) ELISA Kit
Ask
View Details abx252822-03 10x 96 Tests
Human Nuclear Mitotic Apparatus Protein 1 (NUMA1) ELISA Kit
Ask
View Details 