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EGFR-IN-24

EGFR-IN-24, a potent EGFR inhibitor, shows inhibition against EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S), respectively[1].

Product Specifications

CAS Number

2757548-54-0

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-24.html

Purity

98.71

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=C(C=NC=C1)C2=NC(C)=CC(C(NC3=NC4=CC(C5CCN(CC5)C)=CC=C4N3CC(C)(O)C)=O)=C2F

Molecular Formula

C30H35FN6O3

Molecular Weight

546.64

References & Citations

[1]Novel benzimidazole compound. WO2022002100A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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