EGFR-IN-24
EGFR-IN-24, a potent EGFR inhibitor, shows inhibition against EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S), respectively[1].
Product Specifications
CAS Number
[2757548-54-0]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-24.html
Purity
98.71
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C=NC=C1)C2=NC(C)=CC(C(NC3=NC4=CC(C5CCN(CC5)C)=CC=C4N3CC(C)(O)C)=O)=C2F
Molecular Formula
C30H35FN6O3
Molecular Weight
546.64
References & Citations
[1]Novel benzimidazole compound. WO2022002100A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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